Medical Definition of Short- term memory. Short- term memory: A system for temporarily storing and managing information required to carry out complex cognitive tasks such as learning, reasoning, and comprehension. Short- term memory is involved in the selection, initiation, and termination of information- processing functions such as encoding, storing, and retrieving data. One test of short- term memory is memory span, the number of items, usually words or numbers, that a person can hold onto and recall. At the end of a sequence, the person being tested is asked to recall the items in order. The average memory span for normal adults is 7. Short- term memory is also termed recent or working memory. Last Editorial Review: 5/1. Back to Med. Terms online medical dictionary A- Z List. Need help identifying pills and medications? Use the pill finder tool on Rx. Eight Ways to Improve Cognition in Bipolar Disorder. Chris Aiken, MD. RESEARCH UPDATEThe most troublesome statement in Goodwin and Jamison’s Manic- Depressive Illness may be this: “Complete symptomatic remission does not ensure functional recovery.”1 This is no small problem. For some 3. 0% to 6. There’s a third pole that needs to be addressed for that to happen: cognitive symptoms. These often persist even when patients are euthymic, and they range from problems with memory and attention to more subtle deficits such as picking up on social cues and making wise decisions. The steps below, culled from clinical experience and a systematic literature review, should help you guide your patients toward a fuller recovery. Patients usually become aware of cognitive problems as their mood starts to lift. Unless they are prepared for that disappointment, there is a risk they may blame their medications and stop treatment. Adjust medications carefully. Cognitive side effects tend to be dose- dependent, so a careful dose reduction can often clarify whether a medication is contributing to the problem. Choose mood stabilizers with a favorable cognitive profile. Brain health 25 Ways to Make Your Brain More Efficient We show you how to train your brain to be smarter, faster and better than ever. Lamotrigine stands out here. Although it can cause word- finding difficulties, lamotrigine improves multiple areas of cognition, according to large open- label studies and a post- hoc analysis of controlled trials. Two studies from 2. A review found no clear evidence of cognitive side effects from lithium,6 and a randomized trial showed that lithium improves verbal fluency (or at least doesn’t worsen it as much as quetiapine, which was the comparator arm in this study that followed 6. There are still a few cognitive pitfalls with lithium, including the fact that these optimistic results may not apply to all patients. Cognition may be impaired because of subclinical hypothyroidism in patients who take lithium,6 and optimizing thyroid- stimulating hormone levels can help (a good target is 2. IU/m. L). 8 Lithium can also slow motor speed, and some patients interpret that slowing as a cognitive effect. The Bubble is created by these online companies to please and coddle you with content you already like and know, so their advertising and sales will benefit by your. Subscribe to Print: Get our Best Deal! Get a print subscription to Reader's Digest and instantly enjoy free digital access on any device. Curious to know more about your brain? Try the Healthy Brain Test to learn how diet, exercise, and sleep quality can affect brain health. Also try these working. Cognitive side effects tend to be worse for valproate, carbamazepine, and possibly the atypical antipsychotics, but all of these findings vary widely by study, by patient, and even by genetics. In practice, that means it can take a lot of custom tailoring to get it right. There will certainly be patients whose cognition is worse on lithium and better on valproate, though the research may favor lithium on average. In order of importance, I emphasize: sleep, exercise, and diet. A large body of research supports a role for each of these in cognition and mood, though specific studies in bipolar disorder are scarce. A good dose of exercise is 3. For up to 60% of patients with bipolar disorder, simply treating their mood symptoms is not enough to help them return to a full life. National Geographic Executive World Wall Map (From 24.95) History Of Europe, The Major Turning Points Map 1983 (From 49.95) World War II in Europe Wall Map (From 85.00). Neurofeedback allows you to create healthy brainwave states on demand. It’s used to treat a host of mental and physical disorders like anxiety, ADHD & more. Train Your Brain With Exercise. Not only is exercise smart for your heart and weight, but it can make you smarter and better at what you do. Lowering saturated fats and simple sugars is the most important dietary change. The MIND diet is a nice blend of several approaches that have research support for cognition (it stands for . Therapy. Functional Remediation Therapy is a new approach in which patients practice exercises in a group setting to improve their cognitive and social skills. It appears better at restoring functioning than directly improving cognition—but then again, wasn’t that the goal we started out with here? Still, the effect sizes are small, and only 2 out of 3 trials were positive. Some of these groups used web- based trainings between sessions, and the programs they chose are available at: www. Augmentation. Ashwagandha is an Indian form of ginseng that has neuroprotective effects on the hippocampus. In patients with euthymic bipolar disorder, it improved memory, reaction time, and social cognition in a randomized, placebo- controlled trial (n = 5. Look for products with the Sensoril formulation, as that was the type used in the study (target dose, 5. Two other agents that are helpful in bipolar depression, modafinil and omega- 3 fatty acids, are worth considering. Their cognitive benefits are not known in bipolar disorder, but are well- documented in non- affective populations. I’ve seen good results with modafinil and armodafinil, and a trial is underway that will test whether that observation passes the muster of placebo- control. That reminds me: There’s a long list of treatments that generated initial hope but did not pan out in controlled trials. These include 3 that improve bipolar depression but not cognition (pramipexole, N- acetylcysteine, and methylene blue); and several Alzheimer agents (donepezil and galantamine, though galantamine did help memory during ECT). Future directions to look for include intranasal insulin, which is undergoing phase II trials for Alzheimer disease and has a positive study for cognition in bipolar,1. Pay attention to substance use. Cognition is worse in those with dual diagnosis,2 and in the case of cocaine there is a natural treatment that can improve mood, cognition, and sobriety. Citicoline is a neuroprotective agent with 2 positive controlled trials in bipolar with cocaine abuse, and another in unipolar and bipolar with methamphetamine use. It is well- tolerated and available through online retailers (target dose, 1. Test for herpes simplex virus- 1 (HSV- 1). Cognition is significantly worse in patients with bipolar disorder who are seropositive for this common virus, and antiviral therapy can help. Valacyclovir improved several cognitive measures in this population in a randomized, double- blind, placebo- controlled trial (n = 6. That’s a start, but we clearly need more research in this area. It’s also a start for me. Jim Phelps, MD, who created this column a few years back, has generously invited me to join him in the adventure. We’ll be scouring the research to bring you new and forgotten findings in bipolar, and sharing our passion for the humanistic side of this all- too- human disorder. In an upcoming column, we’ll delve deeper into cognition with a how- to- guide on Functional Remediation Therapy.
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